. Author manuscript; available in PMC: 2013 Mar 2.

Published in final edited form as: J Proteome Res. 2012 Feb 7;11(3):1897–1912. doi: 10.1021/pr2011022

Table 1.

Patient charact en sties

	NPl	NP2	NP3	NP4	NP5	NP6	NP7	NP8	NP9	CP1	CP2	CP3	CP4	CP5	CP6	CP7	CP8	CP9
Gender	male	male	male	female	female	female	male	female	male	male	female	male	female	male	male	female	female	female
Age (years)	55	53	48	30	32	30	23	55	56	42	44	41	49	58	68	64	61	53
Race	white	white	white	white	white	white	white	white	Hispanic	white	white	Hispanic	white	white	white	white	white	white
Smoker	−	+	+	−	−	−	−	−	−	−	+	+	+	+	+	+	−	+
Alcohol	+	−	+	−	−	−	−	−	−	−	−	+	+	−	+	+	–	+
TIGAR-O	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	G	G	T	T	I	T	T	I	T
Symptoms	pain	pain	pain, weight loss	Pain, Diarrhea	pain	pain	pain	diarrhea	pain	pain, recurrent pancreat it is	pain, recurrent pancreat it is	pain	pain	pain	pain	none	weight loss, pain	pain
CT Scan Findings	none	none	none	none	none	none	none	none	none	calcifications	calcifications, dilated main duct	calcifications	n/a	calcifications	calcifications, dilated main duct, atrophy	dilated duct, calcifications, atrophy	calcifications, dilated duct, dilated	calcifications, cyst
CT Grade	normal	n/a	normal	n/a	normal	n/a	normal	normal	normal	definite	definite	definite	n/a	definite	definite	definite	definite	definite
EUS Score	1	4	2	n/a	4	2	3	1	n/a	5	5	n/a	7	n/a	5	n/a	8	6
ERCP findings	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	dilated ducts & side branch, stones	n/a	n/a	n/a	n/a	n/a	n/a
ERCP grade	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	IV	n/a	n/a	n/a	n/a	n/a	n/a
MRI grade	n/a	0	n/a	0	0	0	0	0	0	IV	IV	IV	III	IV	IV	IV	IV	IV
CP based on imaging	−	−	−	−	−	−	−	−	−	+	+	+	+	+	+	+	+	+
Peak HCO₃⁻	80	84	101	115	81	90	84	92	114	60	26	22	41	22	39	37	54	38
Secretory dysfunction	−	−	−	−	−	−	−	−	−	+	+	+	+	+	+	+	+	+
Classification	A	A	A	A	A	A	A	A	A	D	D	D	D	D	D	D	D	D

TIGAR-O: T, Toxic-metabolic; I, Idiopathic; G, Genetic; A, Autoimmune; R, Recurrent and severe acute pancreatitis; O, Obstructive. EUS scores: 0–2 is normal 3–4 is equivocal, >5 is definite CP. ERCP Grade (Cambridge classification): normal=0, equivocal=I, mild=II, moderate=III, severe=IV. MRI/MRCP Grade (Cambridge classification: normal=0, equivocal=I, mild=II, moderate=III, severe=IV). Secretory dysfunction: yes (+) <80, no (−) ≥80. Classification of patient: A=healthy, B=Equivocal (Cambridge II, EUS 0–2), C=moderate (Cambridge III, EUS 3–4),D=severe (Cambridge IV, EUS ≥5), E=acute recurrent. n/a: not available; CP, chronic pancreatitis; NP, non-pancreatitis controls.