Table 2.
Proteins identified in all 18 samples.
spectral counts |
||||||||
---|---|---|---|---|---|---|---|---|
Protein | IPI # | total NP | total CP | avg. NP | avg. CP | Bayes Factor | Fold Change | Statistically significant difference |
A2M Alpha-2-macroglobulin | IPI00478003.1 | 2548 | 3075 | 283.11 | 341.67 | 0.00 | 1.18 | no |
ALB Isoform 1 of Serum albumin | IPI00745872.2 | 10452 | 13709 | 1161.33 | 1523.22 | 3.88 | 1.62 | no |
AMBP Protein AMBP | IPI00022426.1 | 70 | 194 | 7.78 | 21.56 | 468.36 | 2.48 | |
AMY1C;AMY1B;AMY1A;AMY2A Alpha-amylase 1 | IPI00300786.1 | 5353 | 2529 | 594.78 | 281.00 | 284.76 | 2.07 | |
AMY1C;AMY1B;AMY1A;AMY2A Pancreatic alpha-amylase | IPI00025476.1 | 9488 | 4003 | 1054.22 | 444.78 | 2.67E+06 | 2.33 | |
AMY2B Alpha-amylase 2B | IPI00021447.1 | 8215 | 3424 | 912.78 | 380.44 | 6231.48 | 2.44 | |
ANPEP Aminopeptidase N | IPI00221224.6 | 834 | 1417 | 92.67 | 157.44 | 6.58 | 2.17 | no |
Anti-(ED-B)scFV | IPI00915411.4 | 239 | 461 | 26.56 | 51.22 | 25.34 | 1.88 | |
C3 Complement C3 | IPI00783987.2 | 1339 | 2757 | 148.78 | 306.33 | 8.35E+07 | 4.34 | |
cDNA FLJ78387 | IPI00876888.1 | 1252 | 1542 | 139.11 | 171.33 | 0.38 | 1.35 | no |
CEL carboxyl ester lipase precursor | IPI00099670.2 | 1898 | 1202 | 210.89 | 133.56 | 2237.61 | 2.38 | |
CLCA1 Calcium-activated chloride channel regulator 1 | IPI00014625.3 | 438 | 664 | 48.67 | 73.78 | 12.92 | 1.66 | |
CPA1 Carboxypeptidase A1 | IPI00009823.3 | 8474 | 3610 | 941.56 | 401.11 | 6.63E+07 | 2.28 | |
CPB1 Carboxypeptidase B | IPI00009826.2 | 5599 | 2537 | 622.11 | 281.89 | 9.38E+05 | 2.37 | |
CTRB1 Chymotrypsinogen B | IPI00015133.1 | 2323 | 1149 | 258.11 | 127.67 | 3.01E+04 | 2.33 | |
CTRB2 chymotrypsinogen B2 | IPI00515087.2 | 4055 | 1781 | 450.56 | 197.89 | 1.09E+05 | 2.14 | |
CTRC Chymotrypsin-C | IPI00018553.1 | 2049 | 793 | 227.67 | 88.11 | 2.45E+04 | 2.71 | |
DCD Dermcidin | IPI00027547.2 | 120 | 158 | 13.33 | 17.56 | 1.67 | 1.30 | no |
DMBT1 Isoform 4 of Deleted in malignant brain tumors 1 protein | IPI00418512.5 | 412 | 175 | 45.78 | 19.44 | 26.37 | 1.89 | |
ELA2A Elastase-2A | IPI00027722.1 | 5087 | 2780 | 565.22 | 308.89 | 87.38 | 1.94 | |
ELA3A Elastase-3A | IPI00295663.1 | 3142 | 1328 | 349.11 | 147.56 | 624.24 | 2.52 | |
ELA3B Elastase-3B | IPI00307485.3 | 1699 | 637 | 188.78 | 70.78 | 1987.17 | 3.13 | |
FCGBP IgGFc-binding protein | IPI00242956.5 | 986 | 1323 | 109.56 | 147.00 | 8.72 | 1.45 | no |
GP2 Isoform Alpha of Pancreatic secretory granule membrane major | IPI00914943.1 | 1678 | 438 | 186.44 | 48.67 | 5.74E+09 | 5.98 | |
HBA1;HBA2 Hemoglobin subunit alpha | IPI00410714.5 | 597 | 480 | 66.33 | 53.33 | 0.72 | 1.31 | no |
HBB Hemoglobin subunit beta | IPI00654755.3 | 898 | 904 | 99.78 | 100.44 | 4.59 | 1.39 | no |
Ig kappa chain V-I region DEE | IPI00387025.1 | 73 | 104 | 8.11 | 11.56 | 3.83 | 1.41 | no |
IGHA1;IGHV3OR16-13 IGHA1 protein | IPI00061977.1 | 1539 | 2264 | 171.00 | 251.56 | 0.96 | 1.39 | no |
IGHA2 IGHA2 protein | IPI00783993.1 | 881 | 1698 | 97.89 | 188.67 | 41855.83 | 2.76 | |
IGHG1 IGHG1 protein | IPI00448925.3 | 1371 | 1700 | 152.33 | 188.89 | 3.01 | 1.44 | no |
IGHG2 IGHG2 protein | IPI00784807.1 | 447 | 496 | 49.67 | 55.11 | 4.47 | 1.22 | no |
IGHG2 Putative uncharacterized protein DKFZp686I04196 | IPI00399007.5 | 894 | 896 | 99.33 | 99.56 | 0.23 | 1.18 | no |
IGHM IGHM protein | IPI00472610.2 | 1801 | 2102 | 200.11 | 233.56 | 2.76 | 1.25 | no |
IGHV4-31 Putative uncharacterized protein DKFZp686G11190 | IPI00784842.1 | 699 | 1148 | 77.67 | 127.56 | 22.10 | 1.65 | |
IGJ immunoglobulin J chain | IPI00178926.2 | 236 | 344 | 26.22 | 38.22 | 10.86 | 1.44 | |
IGKC IGKC protein | IPI00430847.1 | 902 | 1677 | 100.22 | 186.33 | 2.14 | 1.60 | no |
IGKV1-5 IGKV1-5 protein | IPI00430820.1 | 290 | 1038 | 32.22 | 115.33 | 378.57 | 2.32 | |
IGKV2-24 IGKV2-24 protein | IPI00440577.3 | 1365 | 1956 | 151.67 | 217.33 | 114.60 | 1.54 | |
IGKV4-1 Similar to Ig kappa chain V–IV region precursor | IPI00026197.7 | 81 | 93 | 9.00 | 10.33 | 1.08 | 1.16 | no |
Immunglobulin heavy chain variable region | IPI00783287.1 | 164 | 194 | 18.22 | 21.56 | 0.58 | 1.30 | no |
JUP cDNA FLJ60424, highly similar to Junction plakoglobin | IPI00789324.3 | 212 | 260 | 23.56 | 28.89 | 1.54 | 1.18 | no |
LOC100126583 cDNA FLJ41981 fis, clone SMINT2011888 | IPI00784830.1 | 1650 | 2420 | 183.33 | 268.89 | 384.12 | 1.56 | |
LOC100133739 Putative uncharacterized protein DKFZp686C15213 | IPI00426051.3 | 428 | 843 | 47.56 | 93.67 | 498.98 | 1.93 | |
LOC401847 similar to hCG1793095 | IPI00888191.1 | 250 | 304 | 27.78 | 33.78 | 0.62 | 1.31 | no |
LOC642131 similar to hCG1812074 | IPI00887113.1 | 55 | 80 | 6.11 | 8.89 | 2.31 | 1.36 | no |
Myosin-reactive immunoglobulin heavy chain variable region | IPI00783024.1 | 200 | 322 | 22.22 | 35.78 | 93.95 | 1.63 | |
ORM1 Alpha-1-acid glycoprotein 1 | IPI00022429.3 | 405 | 476 | 45.00 | 52.89 | 0.85 | 1.19 | no |
ORM2 Alpha-1-acid glycoprotein 2 | IPI00020091.1 | 184 | 231 | 20.44 | 25.67 | 0.88 | 1.37 | no |
PEPD Xaa-Pro dipeptidase | IPI00257882.7 | 140 | 176 | 15.56 | 19.56 | 1.02 | 1.06 | no |
PIGR Polymeric immunoglobulin receptor | IPI00004573.2 | 1807 | 2364 | 200.78 | 262.67 | 1.96 | 1.24 | no |
PNLIP Pancreatic triacylglycerol lipase | IPI00027720.1 | 5785 | 2729 | 642.78 | 303.22 | 1.44E+09 | 2.25 | |
PRSS1 Trypsin-1 | IPI00011694.1 | 2464 | 1533 | 273.78 | 170.33 | 20.90 | 1.77 | |
PRSS2 Protease serine 2 isoform B | IPI00011695.8 | 1300 | 566 | 144.44 | 62.89 | 54.10 | 1.79 | |
PRSS3 Isoform A of Trypsin-3 | IPI00015614.4 | 1336 | 804 | 148.44 | 89.33 | 2175.75 | 2.15 | |
PRSS7 Enteropeptidase | IPI00023788.1 | 422 | 585 | 46.89 | 65.00 | 2.94 | 1.33 | no |
Putative uncharacterized protein | IPI00807428.1 | 1289 | 1230 | 143.22 | 136.67 | 0.77 | 1.04 | no |
REG1A Lithostathine-1-alpha | IPI00009027.1 | 645 | 284 | 71.67 | 31.56 | 58.20 | 2.03 | |
Rheumatoid factor C6 light chain | IPI00829956.1 | 77 | 100 | 8.56 | 11.11 | 1.40 | 1.29 | no |
SCFV Single-chain Fv | IPI00748998.1 | 331 | 464 | 36.78 | 51.56 | 3.95 | 1.34 | no |
SERPINA1 Isoform 1 of Alpha-1-antitrypsin | IPI00553177.1 | 3075 | 3021 | 341.67 | 335.67 | 4.51 | 1.00 | no |
SERPINA3 cDNA FLJ35730 fis | IPI00550991.3 | 544 | 479 | 60.44 | 53.22 | 1.46 | 1.01 | no |
SERPINC1 Antithrombin III variant | IPI00032179.2 | 290 | 257 | 32.22 | 28.56 | 0.63 | 1.04 | no |
SERPING1 Plasma protease C1 inhibitor | IPI00291866.5 | 260 | 366 | 28.89 | 40.67 | 1.72 | 1.43 | no |
SI Sucrase-isomaltase, intestinal | IPI00221101.3 | 671 | 849 | 74.56 | 94.33 | 15.02 | 1.30 | |
Similar to Elastase-3A precursor | IPI00921065.1 | 1609 | 665 | 178.78 | 73.89 | 2997.68 | 2.98 | |
Single-chain Fv | IPI00470652.1 | 361 | 401 | 40.11 | 44.56 | 0.91 | 1.16 | no |
TF Serotransferrin | IPI00022463.1 | 2806 | 3503 | 311.78 | 389.22 | 214.72 | 1.73 | |
TTR Transthyretin | IPI00022432.1 | 284 | 354 | 31.56 | 39.33 | 0.70 | 1.02 | no |
UGa8H | IPI00828099.1 | 275 | 282 | 30.56 | 31.33 | 0.37 | 1.08 | no |
IPI #, international protein index number; avg., average; CP, chronic pancreatitis; NP, non-pancreatitis controls.