Table 8.
Common pancreatic enzymes that are down-regulated in chronic pancreatitis.
| Protein | IPI | #NP | #CP | Bayes Factor | Fold Change higher in NP |
|---|---|---|---|---|---|
| AMY1C;AMY1B;AMY1A;AMY2A Alpha-amylase 1 | IPI00300786.1 | 9 | 9 | 284.76 | 2.07 |
| AMY1C;AMY1B;AMY1A;AMY2A Pancreatic alpha-amylase | IPI00025476.1 | 9 | 9 | 2.67E+06 | 2.33 |
| CTRB1 Chymotrypsinogen B | IPI00015133.1 | 9 | 9 | 3.01E+04 | 2.33 |
| CTRB2 chymotrypsinogen B2 | IPI00515087.2 | 9 | 9 | 1.09E+05 | 2.14 |
| CTRC Chymotrypsin-C | IPI00018553.1 | 9 | 9 | 2.45E+04 | 2.71 |
| ELA2A Elastase-2A | IPI00027722.1 | 9 | 9 | 87.38 | 1.94 |
| ELA3A Elastase-3A | IPI00295663.1 | 9 | 9 | 624.24 | 2.52 |
| ELA3B Elastase-3B | IPI00307485.3 | 9 | 9 | 1987.17 | 3.13 |
| PLA2G1B Phospholipase A2 | IPI00021792.1 | 9 | 8 | 7961.39 | 3.19 |
| PNLIP Pancreatic triacylglycerol lipase | IPI00027720.1 | 9 | 9 | 1.44E+09 | 2.25 |
| PNLIPRP2 pancreatic lipase-related protein 2 | IPI00005924.4 | 9 | 8 | 39.47 | 3.43 |
| PRSS1 Putative trypsin-6 | IPI00169276.2 | 9 | 8 | 3690.34 | 2.12 |
| PRSS2 Protease serine 2 isoform B | IPI00011695.8 | 9 | 9 | 54.10 | 1.79 |
| PRSS3 Isoform A of Trypsin-3 | IPI00015614.4 | 9 | 9 | 2175.75 | 2.15 |
| RP11-265F14.2 Elastase-2B | IPI00027723.2 | 9 | 8 | 34.73 | 2.00 |
| RP11-265F14.2 Pancreatic elastase IIB | IPI00746692.3 | 5 | 0 | -- | -- |
| Similar to Elastase-3A precursor | IPI00921065.1 | 9 | 9 | 2997.68 | 2.98 |
IPI, international protein index; #NP, number of the non-pancreatitis cohort samples in which the specified protein was present (maximum = 9); #CP, number of chronic pancreatitis cohort samples in which specified protein was present (maximum = 9).