Figure 2.

Absence of NSP protects against anti-MPO antibody–induced NCGN. Urine analysis and renal histologic assessment in mice 8 weeks after transplantation with WT, NE^−/−/PR3^−/−, or NE^−/−/CG^−/− bone marrow: (A) dipstick analysis and (B) renal histologic assessment. Glomerular crescents and necrosis are expressed as the mean percentage of glomeruli with crescents and necrosis. (C) Glomerular neutrophil (PMN) and monocyte/macrophage (MoMa) influx are expressed as the percentage of glomeruli with PMN or MoMa infiltration. (D) Absolute number of infiltrating cells per glomerulus. *P<0.05.