Table 1.
Baseline characteristics of patients with T2D according to outcome during 8–12 years of follow-up
| Baseline Characteristic | Outcome | P Value | ||||
|---|---|---|---|---|---|---|
| Alive (n=267) | ESRD (n=59) | Deceased (n=84) | Alive Compared with ESRD | Alive Compared with Deceased | ESRD Compared with Deceased | |
| Male | 54.7 | 47.5 | 65.6 | 1.00 | 0.89 | 0.35 |
| Age (yr) | 54±10 | 59±8 | 60±7 | 0.003 | <10−5 | 1.00 |
| Body mass index (kg/m2) | 29.7±5.9 | 31.5±7.1 | 29.4±6.5 | 1.00 | 1.00 | 1.00 |
| Systolic BP (mmHg) | 134±17 | 143±20 | 134±18 | 0.013 | 1.00 | 0.21 |
| Serum cholesterol (mg/dl)a | 229±49 | 241±56 | 227±45 | 1.00 | 1.00 | 1.00 |
| Duration of diabetes (yr) | 12±8 | 17±7 | 16±8 | 10−4 | 10−3 | 1.00 |
| HbA1c | 8.3±1.7 | 8.9±1.6 | 8.6±1.6 | 0.65 | 1.00 | 1.00 |
| AER (μg/min) | 20 (12, 66) | 623 (321, 1579) | 72 (22, 217) | <10−30 | <10−7 | <10−30 |
| eGFR (ml/min per 1.73 m2) | 100±27 | 61±31 | 90±30 | <10−30 | 0.09 | <10−6 |
| Treated with insulin | 51.5 | 86.4 | 73.8 | <10−4 | 0.004 | 0.75 |
| Treated with RASi/AHTN | 45.1 | 64.3 | 50.7 | 0.11 | 1.00 | 1.00 |
Data are mean ± SD, median (25th, 75th percentiles), or percentage. The 3×2 chi-squared or ANOVA test was used. Bonferroni correction for the number of clinical variables (n=11). RASi/AHTN, renin-angiotensin system inhibitors and/or other antihypertensive agent.
a
To convert values for cholesterol to millimoles per liter, multiply by 0.02586.