Table 4.
Half-maximal inhibitory concentrations of fatty acids on biofilm formation
| Test compound | Structure | IC50 (μM)a |
|
|---|---|---|---|
| L. monocytogenes | S. aureus | ||
| C9:0 |  |
33.2 ± 4.67 | 4.75 ± 1.24 |
| C10:0 |  |
20.8 ± 2.11 | 7.81 ± 1.01 |
| C12:0 |  |
4.10 ± 0.27 | 5.81 ± 0.78 |
| C13:0 |  |
4.34 ± 0.23 | 6.53 ± 0.39 |
| C14:0 |  |
2.50 ± 0.26 | 6.38 ± 0.08 |
| C16:0 |  |
3.39 ± 1.95 | Stimulates |
| C17:0 |  |
Stimulates | 13.8 ± 4.74 |
| C18:0 |  |
Stimulates | 4.02 ± 1.81 |
a
That is, the concentration at which biofilm formation was inhibited by 50% compared to vehicle control samples. “Stimulates” indicates that the IC50 was not detected at the concentrations tested; biofilm formation was >150% at the highest concentration tested (100 μM) compared to vehicle control samples.