Table. Postmortem findings in a harbor porpoise infected with Brucella ceti, Belgium, 2008*.
Sample | Necropsy | Histologic | Immunohistochemistry† | Electron microscopy | Bacteriologic |
---|---|---|---|---|---|
Brain | NS | Slight subacute meningitis | Glial cells | NT | Brucella isolate |
Uterus | Congestion and hyperplasia | Slight subacute endometritis | Mononuclear cells under the endormetrial epithelium | NT | NT |
Mammary gland | Congestion | Well-developed acini with milk | Mononuclear cells between acini, acinar cells, and milk | NT | NT |
Liver | Multifocal red to dark red spots | Coagulative necrosis | Mononuclear cells in portal areas | NT | NT |
Lungs | Multifocal acute necrotizing thrombo-embolic pneumonia | Acute purulent pneumonia, severe subacute to chronic interstitial pneumonitis | Mononuclear cells and nematode larvae | NT | Brucella isolate |
Lymph nodes | Hyperplasia | Lymphoid depletion | Mononuclear cells near the capsule | NT | NT |
Skin and genital split | Multiple acute to chronic ulcers | Acute ulcerative dermatitis with ballooning degeneration | Balloon degenerated epithelial cells and inflammatory infiltrate | Intracellular coccoid bacteria (genital ulcer) | NT |
Spleen | Hypoplasia | Lymphoid depletion | Mononuclear cells near the splenic capsule and between splenic corpuscles | NT | NT |
*NS, not significant; NT, not tested. †With polyclonal antibody against B. melitensis.