Table 2.
Diagnostic value of Kyn, Trp, and IDO activity to predict mortality in PTB patients
| Predictor | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| IDO (mM/M) | ||||
| 50 | 97.4 | 32.6 | 29.5 | 97.8 |
| 76.7 | 87.2 | 66.7 | 43.0 | 94.7 |
| 100 | 64.1 | 78.5 | 46.3 | 88.3 |
| 150 | 51.3 | 93.3 | 69.0 | 86.9 |
| 200 | 41.0 | 100 | 100 | 85.4 |
| Kyn (μM) | ||||
| 3.0 | 92.3 | 48.9 | 34.3 | 95.7 |
| 3.75 | 82.1 | 63.0 | 39.0 | 92.4 |
| 5.0 | 56.4 | 81.5 | 46.8 | 86.6 |
| 6.0 | 46.2 | 91.1 | 60.0 | 85.4 |
| 7.0 | 30.8 | 94.8 | 63.2 | 82.6 |
| Trp (μM) | ||||
| 30 | 38.5 | 94.1 | 65.2 | 84.1 |
| 40 | 56.4 | 78.5 | 43.1 | 86.2 |
| 49 | 76.9 | 58.5 | 34.9 | 89.8 |
| 60 | 89.7 | 31.9 | 27.6 | 91.5 |
| 70 | 100 | 14.8 | 25.3 | 100 |
| CRP (mg/dl) | ||||
| 2.58 | 84.6 | 56.3 | 35.9 | 92.7 |
| 5.0 | 64.1 | 70.4 | 38.5 | 87.2 |
| 7.5 | 59.0 | 83.7 | 51.1 | 87.6 |
| 10 | 41.0 | 91.1 | 57.1 | 84.2 |
| 15 | 23.1 | 97.0 | 69.2 | 81.4 |