Table 7.
Comparison of two IFN-γ ELISPOT assays and sputum acid-fast staining for patients with PTB
| IFN-γ ELISPOT assay and result | No. of samples with sputum acid-fast staining resulta |
P valueb | ||
|---|---|---|---|---|
| Positive | Negative | Total | ||
| E6+E7 | ||||
| Positive | 27 | 34 | 61 | 4.90 × 10−5 |
| Negative | 7 | 13 | 20 | |
| Total | 34 | 47 | 81 | |
| E6+E7+C14 | ||||
| Positive | 25 | 36 | 61 | 5.43 × 10−9 |
| Negative | 0 | 4 | 4 | |
| Total | 25 | 40 | 65 | |
a
Some patients who appeared to be negative by sputum acid-fast staining could be detected by the two IFN-γ ELISPOT assays. A higher detection sensitivity was found for the E6+E7 IFN-γ ELISPOT assay and the E6+E7+C14 IFN-γ ELISPOT assay than for sputum acid-fast staining (P < 0.05).
b
Calculated by χ2 test.