Table 4.
Mutations that suppress the trxA trxC grxA nrdH strainsa
| Strain | Gene in which mutation was found | Amino acid change |
|---|---|---|
| RO36 suppressors | ||
| MAF173 | dnaA | A345G |
| MAF174 | dnaA | S203T |
| MAF175 | dnaA | N346D |
| MAF176 | dnaA | S331P |
| MAF177 | hda | F85V |
| RO34 | dnaA | A345S |
| RO52 | dnaA | T174P |
| RO51 | dnaN | G157C |
| NK21 suppressors | ||
| NK111 | dnaN | N156S |
| NK113 | dnaA | A362P |
a
Suppressor mutations in RO36 (trxA trxC grxA nrdH) and NK21 [trxA trxC grxA nrdH grxC(M43V)] were identified as described in Materials and Methods. The mutations in RO34, RO52, and RO51 were identified previously by Ortenberg et al. (19).