Table 5.
Characteristics of P. aeruginosa PAO-1 transposon mutantsa
| Mutant | Gene | Description | MIC (μg/ml) |
Carbohydrate and amino acid auxotrophies | |
|---|---|---|---|---|---|
| TOB | FOF | ||||
| PAO-1 | Parent strain, burn wound | 0.5 | 128 | None | |
| PA2291 | Glucose-sensitive porin | 1.0 | 128 | ND | |
| PA3186 | oprB | Outer membrane porin OprB precursor | 1.0 | 128 | Glycerol |
| PA0427 | oprM | Outer membrane protein OprM precursor | 0.125 | 128 | None |
| PA2018 | mexY | RND efflux membrane fusion protein | 0.25 | 128 | None |
| PA2019 | mexX | RND multidrug efflux transporter | 0.25 | 128 | ND |
| PA2020 | mexZ | Transcriptional regulator | 1.0 | 128 | None |
| PA5235 | glpT | Glycerol-3-phosphate transporter | 0.5 | 4096 | G3P |
a
ND, not determined; FOF, fosfomycin; TOB, tobramycin.