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PYD levels in vaginal fluid at the ectocervix (proximal) (A) and introitus (distal) (B) for PYD2 IVRs and PYD1 IVRs. n = 2 animals per group, except on days 21 and 28 of 14 wt% PYD2 loading (n = 1). PYD1 and PYD2 levels were below the LLOQ prior to IVR insertion and after IVR removal (days −11 and 38; data not shown).
