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Efficacy of pyrrolamide 4 in an S. pneumoniae lung infection model in mice. Shown are the numbers of S. pneumoniae CFU recovered from the lungs of mice treated with 0, 80, 160, and 320 mg/kg of pyrrolamide 4 administered orally twice per day, every 12 h. The doses shown are the total daily dose. The error bars represent standard errors in the CFU measurements.
