Table 2.
Predictors of quinolone versus trimethoprim-sulfamethoxazole (TMP-SMX) choice among patients prescribed an antibiotic for urinary tract infectiona
| Characteristic | Result (no. [%]) for: |
OR (95% CI) | Adjusted OR (95% CI) | |
|---|---|---|---|---|
| TMP-SMX (n = 2,537) | Quinolone (n = 9,262) | |||
| Indication | ||||
| Cystitis | 2,449 (96.53) | 8,225 (88.80) | Referent | Referent |
| Pyelonephritis | 88 (3.47) | 1,037 (11.20) | 3.51 (2.67–4.61) | 3.71 (2.76–4.98) |
| Age, yr | ||||
| ≥17 to <65 | 1,452 (57.23) | 5,228 (56.45) | Referent | |
| ≥65 | 1,085 (42.77) | 4,034 (43.55) | 1.03 (0.84–1.28) | |
| Sex | ||||
| Male | 366 (14.43) | 1,810 (19.54) | Referent | Referent |
| Female | 2,171 (85.57) | 7,452 (80.46) | 0.69 (0.54–0.89) | 0.71 (0.55–0.90) |
| Region | ||||
| German | 2,142 (84.43) | 7,269 (78.48) | Referent | |
| Latin | 395 (15.57) | 1,993 (21.52) | 1.49 (0.93–2.37) | |
| Attitude of patient | ||||
| Neutral | 2,104 (82.93) | 8,053 (86.95) | Referent | |
| Favoring | 433 (17.07) | 1,209 (13.05) | 0.73 (0.46–1.16) | |
| Yr | ||||
| 2006 | 797 (31.42) | 2,888 (31.18) | Referent | |
| 2007 | 780 (30.74) | 3,221(34.78) | 1.14 (0.95–1.37) | |
| 2008 | 960 (37.84) | 3,153 (34.04) | 0.91 (0.73–1.12) | |
| Physician specialty | ||||
| General practitioner | 1,937 (76.35) | 6,414 (69.25) | Referent | |
| Internal medicine | 600 (23.65) | 2,848 (30.75) | 1.43 (0.88–2.32) | |
| Prescribing rateb | ||||
| Low | 1,763 (69.49) | 5,272 (56.92) | Referent | Referent |
| High | 669 (26.37) | 3,474 (37.51) | 1.74 (1.10–2.74) | 1.75 (1.10–2.77) |
a
Abbreviations: CI, confidence interval; OR, odds ratio; TMP-SMX, trimethoprim-sulfamethoxazole.
b
Total number of prescriptions analyzed for prescribing rate is 11,178. Categories are based on frequency of antibiotic treatment by physician among patients presenting with influenza-like illness.