Table 1.

Overview of in vitro susceptibility of isolates from French Guiana^a

IC50 range	% (no.) of isolates
	CQ	Quin	Mef	Hal	Art	Amo	Lum
Total	100 (700)	100 (698)	100 (684)	100 (690)	100 (600)	100 (370)	100 (280)
High	53.4 (374)	4.7 (33)	20.2 (138)	14.5 (100)	4.8 (29)	4.3 (16)	27 (76)
Intermediate	9.1 (64)	12.8 (89)	21.6 (148)	25.8 (178)	3.4 (20)	5.3 (20)	7.1 (20)
Low	37.4 (262)	82.5 (576)	58.2 (398)	39.7 (412)	91.8 (551)	90.4 (334)	65.8 (184)

^aShown are percentages of isolates classified as resistant, intermediate, and susceptible based on the IC₅₀ of each drug. Three classes were considered for each antimalarial. The IC₅₀ cutoff for each class was as follows: CQ, chloroquine (high [resistant], IC₅₀ of >100 nM; intermediate, 80 < IC₅₀ < 100 nM; low [susceptible], IC₅₀ of <80 nM); Quin, quinine (high [resistant], IC₅₀ of >500 nM; intermediate, 300 < IC₅₀ < 500 nM; low [susceptible], IC₅₀ of <300 nM); Mef, mefloquine (high [resistant], IC₅₀ of >30 nM; intermediate, 15 < IC₅₀ < 30 nM; low [susceptible], IC₅₀ of <15 nM); Hal, halofantrine (high, IC₅₀ of >8 nM; intermediate, 4 < IC₅₀ < 8 nM; low, IC₅₀ of <4 nM); Art, artemether (high, IC₅₀ of >12 nM; intermediate, 8 < IC₅₀ < 12 nM; low, IC₅₀ of <8 nM); Amo, monodesthyl-amodiaquine (high, IC₅₀ of >60 nM; intermediate, 40 < IC₅₀ < 60 nM; low, IC₅₀ of <40 nM); Lum, lumefantrine (high, IC₅₀ of >150 nM; intermediate, 100 < IC₅₀ < 150 nM; low, IC₅₀ of <100 nM).