Table 3.
Strain | β-lactamase |
MIC (μg/ml) |
|||
---|---|---|---|---|---|
Type | Levela | TD-1792 | THRX-169797b | Penicillin G | |
ATCC 25923 | Negative | 0 | 0.015 | 1 | 0.03 |
ATCC 29213 | A | 0.006 | 0.015 | 1 | 1 |
PC1 | A | 0.201 | 0.015 | 1 | 256 |
NCTC9789 | A | 0.088 | 0.015 | 1 | 64 |
22260 | B | 0.024 | 0.015 | 2 | 16 |
V137 | C | 0.034 | 0.03 | 2 | 64 |
FAR19 | D | 0.030 | 0.015 | 1 | 2 |
Activity reported as micromoles of nitrocefin degraded/min/cell mass after incubation (8).
THRX-169797 is the cephalosporin moiety of TD-1792.