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Effect of TD-1792 against MRSA ATCC 33591 on thigh bacterial burden in mice dosed with various total 24-h doses of TD-1792 (0.03 to 1 mg/kg, SC) administered in one, two, or four divided fractions. The abscissa shows the total 24-h dosage in mg/kg, SC, and the ordinate shows the thigh bacterial burden in log10 CFU/g. Data are expressed as means ± SD (n = 5 to 10).
