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. 2012 Mar;56(3):1578–1583. doi: 10.1128/AAC.05382-11

Table 3.

TD-1792 AUC/MIC ratios associated with net bacterial stasis, 1 log10 CFU/g reduction from baseline, and EC90 against MRSA ATCC 33591 in the neutropenic murine thigh animal model

Endpoint Estimate 95% CI
Net bacterial stasis 21.1 17.0–25.3
1 log10 CFU/g reduction from baseline 37.2 26.9–47.5
EC90a 51.8 29.9–73.8
a

EC90, value of the AUC/MIC ratio at which there is 90% of maximal effect.