Table A2. Significance, hazard ratios, and 95% CIs of variables in the 3 models measuring sequelae in children and young adults after infective gastroenteritis*.

Variables in model

Category

Any sequelae

Extragastrointestinal sequelae

p value	HR (95% CI)	p value	HR (95% CI)
Previous history of an enteric infection	Yes	<0.0001	1.642 (1.590–1.695)		<0.0001	1.628 (1.574–1.684)
Sex	Female	<0.0001	0.806 (0.790–0.822)		<0.0001	0.789 (0.772–0.806)
Indigenous status	Aboriginal	<0.0001	1.807 (1.728–1.890)		<0.0001	1.897 (1.810–1.988)
Singleton birth	Yes	0.0071	1.090 (1.024–1.160)		0.0084	1.094 (1.023–1.170)
Year of birth		<0.0001	0.978 (0.976–0.981)		<0.0001	0.989 (0.986–0.991)
Age in years at enteric infection or proxy		<0.0001	0.872 (0.868–0.877)		<0.0001	0.810 (0.805–0.815)
Weight at birth, g	<2,000	<0.0001	1.000		<0.0001	1.000
	2,001–3,000	<0.0001	0.799 (0.747–0.854		<0.0001	0.768 (0.715–0.824)
	3,001–4,000	<0.0001	0.745 (0.698–0.796)		<0.0001	0.706 (0.658–0.756)
	4,001–5,000	<0.0001	0.728 (0.678–0.782)		<0.0001	0.686 (0.636–0.740)
	>5,001	0.0747	0.809 (0.641–1.021)		0.0871	0.808 (0.633–1.032)
Socioeconomic status (SEIFA)	Extremely advantaged	<0.0001	1.000		<0.0001	1.000
	Advantaged	0.1977	1.022 (0.989–1.057)		0.1657	1.026 (0.989–1.064)
	Average	0.0003	1.066 (1.029–1.103)		0.0005	1.069 (1.029–1.111)
	Disadvantaged	<0.0001	1.143 (1.110–1.177)		<0.0001	1.166 (1.129–1.204)
	Extremely disadvantaged	<0.0001	1.112 (1.079–1.146)		<0.0001	1.122 (1.086–1.159)
Accessibility to services	Highly accessible	<0.0001	1.000		<0.0001	1.000
	Accessible	<0.0001	1.183 (1.141–1.227)		<0.0001	1.203 (1.157–1.252)
	Moderately accessible	<0.0001	1.218 (1.175–1.262)		<0.0001	1.257 (1.210–1.306)
	Remote	<0.0001	1.329 (1.260–1.402)		<0.0001	1.410 (1.333–1.492)
	Very remote	<0.0001	1.149 (1.102–1.197)		<0.0001	1.206 (1.154–1.260)
Born in hospital	Yes	<0.0001	0.883 (0.838–0.931)		<0.0001	0.820 (0.776–0.867)
Mother’s region of birth	Australia	<0.0001	1.000		<0.0001	1.000
	New Zealand	0.0006	0.852 (0.778–0.934)		0.0108	0.880 (0.798–0.971)
	United Kingdom	0.0018	0.925 (0.881–0.972)		0.0131	0.935 (0.886–0.986)
	North America	0.1076	0.833 (0.668–1.041)		0.1996	0.853 (0.668–1.088)
	Europe	0.0101	0.886 (0.808–0.972)		0.0106	0.874 (0.788–0.969)
	Eastern Europe, former USSR, and Baltic States	0.3687	0.897 (0.709–1.136)		0.5647	0.926 (0.711–1.204)
	Africa	0.1407	0.912 (0.808–1.031)		0.2897	0.931 (0.816–1.063)
	Central/South America and Caribbean	0.7729	0.964 (0.754–1.233)		0.4821	0.906 (0.687–1.194)
	Melanesia, Micronesia, and Polynesia	0.2428	0.804 (0.558–1.159)		0.2646	0.796 (0.534–1.188)
	Asia	<0.0001	0.593 (0.545–0.645)		0.0000	0.600 (0.546–0.659)
	Middle East	0.3621	0.892 (0.699–1.140)		0.2494	0.855 (0.655–1.116)
Father’s region of birth	Australia	<0.0001	1.000		<0.0001	1.000
	New Zealand	0.0989	0.950 (0.893–1.010)		0.2285	0.960 (0.899–1.026)
	United Kingdom	0.0580	1.033 (0.999–1.069)		0.1773	1.026 (0.989–1.065)
	North America	0.1267	0.910 (0.806–1.027)		0.1727	0.912 (0.799–1.041)
	Europe (N,S, and W)	0.0239	0.934 (0.881–0.991)		0.0083	0.915 (0.857–0.977)
	Eastern Europe, former USSR, and Baltic States	0.1320	0.853 (0.693–1.049)		0.0285	0.768 (0.606–0.973)
	Africa	0.0894	0.924 (0.843–1.012)		0.1606	0.931 (0.843–1.029)
	Central/South America and Caribbean	0.8662	1.019 (0.822–1.261)		0.8923	1.016 (0.803–1.286)
	Melanesia, Micronesia, and Polynesia	0.3944	0.906 (0.721–1.138)		0.5997	0.937 (0.733–1.196)
	Asia	<0.0001	0.847 (0.785–0.914)		<0.0001	0.825 (0.758–0.897)
	Middle East	0.1435	0.857 (0.697–1.054)		0.3362	0.897 (0.718–1.120)
Hospitalization for a concurrent illness	Yes	<0.0001	0.814 (0.766–0.864)		<0.0001	6.671 (5.637–7.893)

*HR, hazard ratio; CI, confidence interval; USSR, Union of Soviet Socialist Republics; –, not applicable.