Fig 7.

Effect of Irf7^−/− on intracellular growth of L. monocytogenes. Growth of L. monocytogenes LO28 was assessed by plating of serial dilutions of cellular lysates at the indicated time points. WT or Irf7^−/− BMDMs were pretreated with IFN-γ for 15 h or left without pretreatment and infected with L. monocytogenes LO28 at a multiplicity of infection of 10. CFU counts represent mean values of six experimental values. The experiment was repeated three times. Data sets were analyzed by Student's t test (two tailed, equal variance). ***, P < 0.001.