Table 1.
Case reports of Staphylococcus intermedius infection in humans
| Case no. | Yr reported | Description (reference) | Site or type of infection | Immune deficiency/underlying illness | Drug susceptibilityc | Antibiotic treatment | Outcome |
|---|---|---|---|---|---|---|---|
| 1–3 | 1989 | Case series of canine-inflicted cellulitis (13) | Skin/soft tissue | None | Two isolates S to PCN, one isolate R to PCN | PCN, amox-clav | Recovered |
| 4 | 1992 | Case report (11) | Endocarditis | HIV | NR | Cloxacillin, gentamicin followed by oral ciprofloxacin and rifampin | NR |
| 5 | 1992 | Case report (2) | Skin/soft tissue | None | R to PCN, tetracycline S to amox-clav, erythromycin, flucloxacillin, gentamicin, sodium fusidate | Amox-clav | Recovered |
| 6–8 | 1994 | Case series of canine-inflicted and non-canine-inflicted wounds (17) | Skin/soft tissue | NRa | NR | NR | NR |
| 9 | 1995 | Case report (17) | Catheter-related bacteremia | Metastatic lung cancer, splenectomy | S to PCN, oxacillin, gentamicin, erythromycin, rifampin, cotrimoxazole, vancomycin | Amox-clav, ciprofloxacin | Recovered |
| 10 | 1999 | Case report (5) | Pneumonia | Diabetes | R to PCN, oxacillin, clindamycin, erythromycin, ofloxacin; S to TMP-SMX, gentamicin, vancomycin | Vancomycin | Recovered |
| 11 | 2000 | Molecular phylogenetic analysis (16) | Otitis externa | None | NR | NR | NR |
| 12 | 2004 | Case report (10) | Mastoiditis | None, but s/pb mastoidectomy | Pansensitive, including PCN | Ofloxacin | Recovered |
| 13, 14 | 2004 | Case series (12) | Skin/soft tissue | Case 13, breast cancer on chemotherapy; case 14, none | Case 13 isolate was pansensitive except to PCN and produced β-lactamase; case 14 isolate was sensitive to all but PCN and tetracycline | NR | NR |
| 15 | 2005 | Case report (1) | Brain abscess | None | R to PCN, methicillin, clindamycin | Vancomycin | Recovered |
| 16 | 2009 | Case report (8) | Sinusitis | None | R to cefazolin, oxacillin, levofloxacin, cotrimoxazole, tetracycline; I to gentamicin; S to vancomycin, linezolid, rifampin | Vancomycin, linezolid | Recovered |
| 17 | 2011 | Case report (7) | Skin abscesses | Hepatitis C | S to oxacillin, ampicillin-sulbactam, cefazolin, TMP-SMX, vancomycin | Vancomycin, amox/clav | Recovered |
a
NR, not reported.
b
s/p, status post.
c
PCN, penicillin; amox-clav, amoxicillin-clavulanate; TMP-SMX, trimethoprim-sulfamethoxazole; R, resistant; I, intermediate; S, susceptible.