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. Author manuscript; available in PMC: 2012 Mar 6.
Published in final edited form as: Curr Alzheimer Res. 2011 Jun;8(4):393–409. doi: 10.2174/156720511795745401

Figure 5. Localization of mutant proteins of PD in the mitochondria in neurons affected by PD.

Figure 5

In PD neurons, mutant proteins of α-synuclein, parkin, PINK1, and DJ1 are associated with mitochondria and cause mitochondrial dysfunction. Complex I activity is inhibited in PD neurons.