Table 4.
Effects of prenatal PCB, DDE and DDT concentrations on overweight at 6.5 years in the total population and in subgroups, according to child sex or fat intakes.
| OC exposure level | PCBs | DDE | DDT | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Subgroup | n | RRa (95% CI) | n | RRa (95% CI) | n | RRa (95% CI) | ||||||||
| Overall (n = 344) | T2b | 118 | 0.97 (0.58, 1.62) | 116 | 1.67 (1.10, 2.55) | 124 | 1.19 (0.76, 1.87) | |||||||
| T3b | 117 | 1.70 (1.09, 2.64) | 115 | 1.28 (0.81, 2.03) | 112 | 1.17 (0.73, 1.88) | ||||||||
| Girls (n = 178) | T2b | 62 | 1.64 (0.72, 3.76) | 61 | 2.64 (1.18, 5.90) | 69 | 0.90 (0.47, 1.73) | |||||||
| T3b | 64 | 2.13 (0.99, 4.57) | 58 | 1.86 (0.75, 4.63) | 57 | 1.16 (0.59, 2.28) | ||||||||
| Boys (n = 166) | T2b | 56 | 0.50 (0.26, 0.97) | 55 | 1.27 (0.69, 2.34) | 55 | 1.96 (1.06, 3.62) | |||||||
| T3b | 53 | 1.43 (0.82, 2.48) | 57 | 1.31 (0.73, 2.38) | 55 | 1.49 (0.73, 3 .05) | ||||||||
| p Sex interactionc | T2 | 0.01 | 0.07 | 0.10 | ||||||||||
| T3 | 0.07 | 0.28 | 0.48 | |||||||||||
| Low fat intake (n = 172) | T2b | 53 | 0.72 (0.36, 1.48) | 56 | 1.65 (0.89, 3.04) | 60 | 1.01 (0.55, 1.85) | |||||||
| T3b | 63 | 1.44 (0.81, 2.56) | 52 | 1.17 (0.60, 2.29) | 60 | 1.08 (0.56, 2.09) | ||||||||
| High fat intake (n = 172) | T2b | 65 | 1.23 (0.58, 2.59) | 60 | 1.89 (0.92, 3.86) | 64 | 2.31 (1.16, 4.58) | |||||||
| T3b | 54 | 1.95 (1.00, 3.82) | 63 | 1.38 (0.72, 2.66) | 52 | 1.62 (0.78, 3.37) | ||||||||
| p Fat intake interactionc | T2 | 0.37 | 0.72 | 0.14 | ||||||||||
| T3 | 0.46 | 0.77 | 0.41 | |||||||||||
| aMultivariable model adjusted for birth weight, previous parity, maternal prepregnancy BMI, maternal education and social class at pregnancy, maternal smoking in pregnancy, maternal age at delivery, and breast-feeding. Stratified models by fat intakes additionally adjusted for diet misreporting. bSecond (T2) or third tertile (T3) compared with first. cTertile-specific p Wald test for interaction. | ||||||||||||||