Table 1.
AP |
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No. of Cells | Diameter, μm | Cell Capacitance, pF | Membrane Potential, mV | Input Resistance, MΩ | Rheobase, pA | Voltage threshold, mV | Amplitude, mV | Duration, ms | MS/Non-MS | |
Control | 9 | 24.4 ± 0.7 | 18.9 ± 1.1 | −54.1 ± 2.6 | 374.7 ± 70.4 | 101.7 ± 6.5 | −26.8 ± 1.4 | 105.6 ± 7.4 | 2.9 ± 0.4 | 2/7 |
CCD | 8 | 23.3 ± 1.4 | 17.3 ± 2.1 | −57.0 ± 4.5 | 346.3 ± 38.4 | 62.5 ± 9.1† | −33.0 ± 1.5* | 103.8 ± 3.7 | 4.1 ± 0.6 | 3/5 |
Values are mean ± SE. CCD, chronic compression; AP, action potential; rheobase, current threshold; MS, number of cells firing multiple (≥2) spikes to current step at 2× rheobase; non-MS, number of cells discharging 1 spike.
P < 0.05 and
P < 0.01 by Student's t-tests (significant differences between control and CCD neurons).