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. Author manuscript; available in PMC: 2012 Mar 6.

Published in final edited form as: Biochemistry. 2010 Nov 2;49(43):9249–9255. doi: 10.1021/bi101291d

Lineweaver-Burke plots demonstrating the inhibition of PdxB by D-2-HGA. A) 4PE vs. D-2-HGA at concentrations of 0 μM (open triangles), 50 μM (open circles), 70 μM (open squares), 300 μM (solid triangles), and 1 mM (solid circles). B) αKG vs. D-2-HGA at concentrations of 0 μM (open triangles), 70 μM (open squares), 300 μM (solid triangles), and 1 mM (solid circles).

Lineweaver-Burke plots demonstrating the inhibition of PdxB by D-2-HGA. A) 4PE vs. D-2-HGA at concentrations of 0 μM (open triangles), 50 μM (open circles), 70 μM (open squares), 300 μM (solid triangles), and 1 mM (solid circles). B) αKG vs. D-2-HGA at concentrations of 0 μM (open triangles), 70 μM (open squares), 300 μM (solid triangles), and 1 mM (solid circles).