Table 2.
Multivariate Analysis of Association of ARID5B SNPs With ALL Susceptibility
Whites |
Hispanics |
||||||
---|---|---|---|---|---|---|---|
SNP ID | OR | 95% CI | P* | SNP ID | OR | 95% CI | P* |
rs10821936 | 2.13 | 1.77 to 2.58 | 2.19 × 10−15 | rs10821936 | 1.92 | 1.50 to 2.45 | 2.14 × 10−7 |
rs7915732† | 2.58 | 1.27 to 3.52 | .0091 |
Abbreviations: ALL, acute lymphoblastic leukemia; ID, identification; OR, odds ratio; SNP, single nucleotide polymorphism.
P values indicate association after adjusting for other SNPs in a forward selection–based multivariate model (see Patients and Methods).
In univariate analyses, rs7915732 was related to ALL susceptibility in Hispanics (P = .059) but not in whites (P = .293).