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. 2012 Jan 9;30(5):497–506. doi: 10.1200/JCO.2011.38.6060

Fig 2.

Fig 2.

(A) Absolute risk of developing breast cancer by age 70 years, stratified by guideline-recommended systemic treatments according to stage, size, and estrogen receptor expression, for BRCA1 mutation carriers who choose risk-reducing strategies including annual breast screening (S) with mammography and magnetic resonance imaging, prophylactic mastectomy (PM), and/or prophylactic oophorectomy (PO) performed at various ages (age in years indicated by number after PM or PO). (B) Absolute risk of developing breast cancer by age 70 years, stratified by guideline-recommended systemic treatments according to stage, size, and estrogen receptor expression, for BRCA2 mutation carriers who choose risk-reducing strategies including S, PM, and/or PO performed at various ages (age in years indicated by number after PM or PO).