Table 4.

Characteristics of Patients With Distant Metastases by HER2 Status

Characteristic	HER2 Status				P
	Concordant(n = 133)		Discordant(n = 35)
	No.	%	No.	%
Age at primary diagnosis, years
Mean	47.04		52.26		.013
SD	11.27		9.42
Menopausal status
Premenopausal	76	57	12	34	.023
Postmenopausal	57	43	22	63
Unknown	0	0	1	3
ER status
Positive	68	51	18	51	.993
Negative	64	48	17	49
Unknown	1	1	0	0
PR status
Positive	45	34	15	43	.368
Negative	85	64	20	57
Unknown	3	2	0	0
Trastuzumab
None	77	58	24	69	.251
Before biopsy	56	42	11	31
Tumor grade
I	0	0	2	6	< .001
II	20	15	10	28
III	107	80	22	63
Unknown	6	5	1	3
Distant metastatic site
Without visceral	46	35	16	45	.225
With visceral	87	65	19	55

Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor; SD, standard deviation.