Table 2.
Univariate and stepwise regression analysis with serum lipocalin-2 concentration as a dependent variable
| Co-variable | Univariate | Stepwise | |||
|---|---|---|---|---|---|
| r | β(SEM) | p value | β(SEM) | p value | |
| Age (years) | 0.000 | -0.002 (0.001) | 0.497 | - | - |
| Sex (male = 1, female = 2) | 0.086 | 0.033 (0.020) | 0.001 | - | - |
| Body mass index (kg/m2) | 0.058 | 0.015 (0.004) | 0.018 | 0.160 (0.004) | < 0.001 |
| Waist circumference (cm) | 0.118 | 0.000 (0.007) | < 0.001 | 0.105 (0.001) | 0.012 |
| Waist/hip ratio | 0.081 | 0.151 (0.580) | 0.005 | - | - |
| Fasting plasma glucose (mmol/l) | 0.107 | 0.011 (0.009) | < 0.001 | - | - |
| 2h OGTT plasma glucose (mmol/l) | 0.066 | 0.005 (0.003) | 0.009 | - | - |
| Log10 fasting serum insulin (μU/ml) | 0.263 | 0.140 (0.050) | < 0.001 | 0.105 (0.045) | 0.007 |
| Log10 HOMA-IR | 0.291 | 0.123 (0.031) | < 0.001 | 0.209 (0.025) | < 0.001 |
| Log10 triacylglycerol (mmol/l) | 0.134 | 0.054 (0.053) | < 0.001 | - | - |
| Total cholesterol (mmol/l) | -0.087 | 0.031 (0.019) | < 0.001 | -0.075 (0.008) | 0.006 |
| HDL- cholesterol (mmol/l) | -0.181 | -0.041 (0.037) | < 0.001 | -0.092 (0.026) | 0.002 |
| LDL- cholesterol (mmol/l) | -0.059 | 0.009 (0.020) | 0.016 | - | - |
| Systolic blood pressure (mmHg) | 0.081 | 0.001 (0.001) | 0.002 | - | - |
| Diastolic blood pressure (mmHg) | 0.101 | 0.000 (0.001) | < 0.001 | - | - |
| CRP (μg/ml) | 0.131 | 0.021 (0.021) | < 0.001 | - | - |
| CXCL5 (pg/ml) | 0.076 | 0.084 (0.026) | 0.003 | 0.08 (0.025) | 0.002 |
| Adiponectin (μg/ml) | -0.095 | 0.015 (0.035) | < 0.001 | - | - |
β, Regression coefficient; r, Pearson correlation coefficient; SEM standard error of mean