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. 2011 Dec 30;11:22. doi: 10.1186/1472-6904-11-22

Table 3.

Outcomes of etomidate vs. control stratified by hydrocortisone use

Etomidate (n = 23) Control (n = 39)
Hydrocortisone Placebo P-Value Hydrocortisone Placebo P-value
N = 14 N = 9 N = 20 N = 19
ICU mortality, No.% 12 (85.7) 9 (100) 0.50 12 (60) 13 (68.4) 0.74
Hospital mortality, No.% 14 (100) 9 (100) 18 (90) 19 (100) 0.49
28-day mortality, No.% 13 (92.9) 8 (88.9) 1.0 18 (90) 15 (79) 0.41
Delta norepinephrine (d2-1) (μ/kg/min) -0.05 ± 0.23 0.15 ± 0.36 0.05 -0.10 ± 0.24 0.08 ± 0.25 0.02
Delta norepinephrine (d3-1) (μ/kg/min) -0.10 ± 0.26 0.31 ± 0.36 0.01 -0.20 ± 0.33 0.06 ± 0.28 0.02
ICU length of stay (days), mean ± SD 13.7 ± 7.2 10.9 ± 8.5 0.23 9.4 ± 5.9 9.3 ± 5.6 0.93
Ventilation-free days, mean ± SD 3.6 ± 5.6 0.2 ± 0.4 0.04 6.2 ± 6.6 5.8 ± 8.5 0.6
Vasopressor-free days, mean ± SD 4.6 ± 6.9 1.1 ± 3.3 0.05 7.1 ± 8.0 3.8 ± 7.5 0.20