Table 2.

Estimated hazard ratios (HRs) and 95% confidence intervals (CIs) from multivariable models for disease-free, overall, and breast cancer–specific survival for black vs nonblack patients with hormone receptor–positive, HER2-negative or unknown disease^*

Model	Variable(s)	HR of breast cancer recurrence or death (95% CI)	HR of death (95% CI)	HR of death from breast cancer (95% CI)
1	Black race	1.66 (1.25 to 2.21); P < .001	1.64 (1.15 to 2.33); P = .006	1.81 (1.23 to 2.68); P = .003
2	Obesity (BMI ≥ 30 kg/m2)	1.24 (1.08 to 1.49); P = .0032	1.40 (1.15 to 1.69); P < .001	1.45 (1.16 to 1.82); P = .0012
3	Black race	1.58 (1.18 to 2.11); P = .0021	1.51 (1.05 to 2.16); P = .025	1.65 (1.11 to 2.46); P = .013
	Obesity	1.22 (1.04 to 1.44); P = .0141	1.35 (1.11 to 1.64); P = .003	1.39 (1.11 to 1.75); P = .005
4	Black race–obesity interaction: Black race vs other and BMI ≥30 kg/m2	1.19 (0.80 to 1.77); P = .3815	1.07 (0.65 to 1.74); P = .800	1.17 (0.68 to 2.01); P = .562
	Black race vs other and BMI <30 kg/m2	2.38 (1.57 to 3.60); P < .001	2.59 (1.56 to 4.32); P < .001	2.85 (1.61 to 5.02); P < .001

^*Other variables in these models include age (<50 vs ≥50 y), number of positive lymph nodes (0 [reference] vs 1–3 vs ≥4), tumor size (≤2 vs >2 cm), surgery (breast-sparing vs mastectomy), and type of hormone therapy used. Hormone therapy was coded as a time-varying variable, and all other variables were coded as time-fixed variables. All P values are two-sided. BMI = body mass index.