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. 2012 Mar 6;7(3):e32145. doi: 10.1371/journal.pone.0032145

Figure 2. Neogenin enhances acute inflammatory peritonitis.

Figure 2

Neo1−/− and WT animals were injected i.p. with NaCl or 1 mg of zymosan A (ZyA) and peritoneal lavage obtained after 8 hours A) Cell count in peritoneal lavage of Neo1−/− and WT animals B) Myeloperoxidase (MPO) activity in peritoneal lavage C) Protein content in peritoneal lavage of Neo1−/− and WT animals D) Representative histological analysis of the peritoneum, the mesenterial fat and cytospin samples of the peritoneal lavage in Neo 1−/− and WT animals 8 hours following intraperitoneal NaCl 0.9% or ZyA injection. Sections prepared with hematoxylin-eosin staining (Magnification ×400, insert ×1000; Data are Mean ± SEM, n = 6 per group, *P<0.05, **P<0.01, ***P<0.001 as indicated).