Table 1.
Top 21 Gene Ontology categories between the YH and the mDC samples
| Gene name | GO ID | NM | GO category | Methylation level of mDC | Methylation level of YH | P value |
|---|---|---|---|---|---|---|
| HELLS | GO:0005524 | NM_018063 | ATP binding | 33.333 | 1.316 | 4.54E-03 |
| MSI1 | GO:0007399 | NM_002442 | nervous system development | 20.833 | 2.632 | 8.23E-03 |
| CEBPE | GO:0046983 | NM_001805 | protein dimerization activity | 23.739 | 9.081 | 5.58E-79 |
| EML2 | GO:0007605 | NM_012155 | sensory perception of sound | 27.621 | 13.554 | 9.63E-12 |
| GLTSCR2 | GO:0005634 | NM_015710 | nuclear | 23.36 | 11.579 | 1.52E-04 |
| TBC1D17 | GO:0005096 | NM_024682 | GTPase activator activity | 25.197 | 3.425 | 3.51E-14 |
| BDH1 | GO:0016491 | NM_203314 | oxidoreductase activity | 22.892 | 11.345 | 6.49E-13 |
| COL23A1 | GO:0016021 | NM_173465 | integral to membrane | 20.896 | 10.081 | 5.73E-03 |
| WASF1 | GO:0030041 | NM_001024936 | actin filament polymerization | 22.215 | 10.467 | 9.32E-23 |
| MYO1G | GO:0016459 | NM_033054 | myosin complex | 21.907 | 8.239 | 5.16E-13 |
| ARMCX2 | GO:0016021 | NM_014782 | integral to membrane | 31.395 | 14.286 | 5.12E-04 |
| MMP21 | GO:0008270 | NM_147191 | zinc ion binding | 9.375 | 33.862 | 1.05E-07 |
| ITGA7 | GO:0016020 | NM_002206 | membrane | 10.879 | 21.88 | 1.39E-11 |
| DHRS12 | GO:0016491 | NM_024705 | oxidoreductase activity | 8.696 | 23.144 | 1.55E-05 |
| AURKC | GO:0016740 | NM_001015878 | transferase activity | 10.256 | 30.769 | 9.17E-03 |
| SOX18 | GO:0006357 | NM_018419 | regulation of transcription from RNA polymerase II promoter | 3.656 | 20.225 | 2.55E-15 |
| CIDEC | GO:0006917 | NM_022094 | induction of apoptosis | 8.333 | 20.098 | 6.22E-04 |
| PF4 | GO:0045653 | NM_002619 | negative regulation of megakaryocyte differentiation | 0 | 22.222 | 3.13E-03 |
| MARCKS | GO:0051015 | NM_002356 | actin filament binding | 5.405 | 30.088 | 4.66E-03 |
| PRAF2 | GO:0016021 | NM_007213 | integral to membrane | 8.333 | 26.02 | 3.00E-03 |
| FAM155B | GO:0016021 | NM_015686 | integral to membrane | 0 | 21.053 | 4.02E-04 |
The methylation level represents the average methylation level of the CpGs in the region. The P value was calculated using the chi-square test.