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. 2012 Mar 6;10(3):e1001276. doi: 10.1371/journal.pbio.1001276

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Viotti et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) EHF-LHF embryos cultured until the ∼4 somite stage. (B and C) Lefty1/2 in control embryos showing wild-type localization in left LPM (white asterisks) and midline (white arrowhead). (D–G) Lefty1/2 expression in embryos cultured in 18 alpha-Glycyrrhetinic acid. No (D and E, 10/14) or weak/restricted signal in left LPM (F and G, 3/14). (H and I) Lefty1/2 in embryos cultured in Mefloquine hydrochloride, exhibiting wild-type localization. A, anterior; D, distal; L, left; P, posterior; Pr, proximal; R, right.