Table 1.
Brain Volumes of 13 22q Deletion Syndrome and Schizophrenia (22qDS-SZ) and 13 Age and Gender Matched Control Subjects, Uncorrected for Total Intracranial Volume
| Mean (SD)
|
||||
|---|---|---|---|---|
| Left Hemisphere
|
Right Hemisphere
|
|||
| 22qDS-SZ Subjects | Controls | 22qDS-SZ Subjects | Controls | |
| Total GM | 304.3 (35.4)c | 362.1 (51.3) | 307.8 (35.3)b | 343.3 (44.9) |
| WM | 247.1 (30.2) | 250.2 (38.8) | 249.3 (31.2) | 265.2 (50.1) |
| CSF | 88.9 (14.0) | 82.2 (16.9) | 88.0 (15.2)b | 75.3 (12.4) |
| Lateral Ventriclesa | 12.7 (4.9)c | 7.4 (3.3) | 12.1 (4.8)d | 5.7 (2.1) |
| Frontal GM | 92.6 (12.9)c | 110.1 (18.7) | 87.4 (15.8)b | 102.5 (13.3) |
| WM | 90.5 (12.2) | 87.0 (15.9) | 104.0 (16.9) | 97.8 (20.8) |
| CSF | 29.2 (5.2) | 26.9 (5.6) | 28.0 (5.9) | 24.9 (4.5) |
| Temporal GM | 61.7 (6.8)c | 75.0 (11.3) | 61.7 (6.2)b | 70.1 (10.2) |
| WM | 33.5 (5.0) | 34.0 (4.7) | 37.1 (6.2) | 40.7 (9.9) |
| CSF | 15.0 (2.7) | 13.6 (2.4) | 13.8 (2.6) | 12.2 (1.8) |
| Parietal GM | 52.1 (6.2)c | 62.4 (7.8) | 55.5 (6.6) | 59.0 (7.2) |
| WM | 50.1 (6.1) | 52.6 (8.8) | 48.5 (4.4)b | 55.1 (9.3) |
| CSF | 15.4 (2.5) | 14.6 (3.7) | 15.5 (3.0) | 13.1 (3.0) |
| Occipital GM | 30.4 (4.2)b | 34.0 (3.6) | 33.4 (4.9) | 32.4 (3.9) |
| WM | 22.9 (3.9) | 23.5 (5.6) | 15.3 (2.8)b | 20.7 (4.5) |
| CSF | 9.9 (2.0) | 9.0 (2.4) | 10.6 (1.9)c | 8.3 (1.8) |
Volumes are presented in cc; CSF, cerebrospinal fluid; GM, gray matter; WM, white matter.
a
N = 14 in each group.
b
p < .05.
c
p < .01.
d
p < .001.