Table 3.
Recent Studies Using Perirenal Implantation
| Article No. | PMID | Author | Year | Cell(s) | Protein | Scaffold | Duration | Results | Animal |
|---|---|---|---|---|---|---|---|---|---|
| 1. | 21427841 | Zhang46 | 2011 | Rat tooth germ cells | BMP2 | Nanoscale B-TCP/collagen particles | 8 Weeks | Mature appearance and organized structure of enamel-dentin like tissue | Rat |
| 2. | 20695775 | Chun47 | 2011 | Embryonic tooth-forming primordia and xenogenic murine apical bud epithelium/human dental pulp stem cell composites | EDTA soluble tooth proteins (ESTP) | Fibrin glue | 4 Weeks | ESTP-treated tooth buds developed normal morphology whereas untreated controls developed abnormally | Mouse |
| 3. | 19078959 | Chan105 | 2009 | Mouse fetal osteoblasts | — | Matrigel | 4 Weeks | Structural similarity to normal bone was identified with regions of cartilaginous, compact, and trabecular bone | Mouse |
| 4. | 19590164 | Lenton45 | 2009 | Embryonic and early postnatal calvarial bone | — | — | 2 Weeks | Structural similarity to normal cranial sutures was identified among transplanted bone | Mouse |
| 5. | 18619727 | Prigozhina107 | 2008 | Mouse MSCs from bone marrow, placenta, or umbilical cord | — | DBM | 2 Weeks | All MSC types showed ectopic bone formation in synergetic recipients | Mouse |
| 6. | 17198881 | Gurevitch45 | 2007 | Mouse BMSCs | — | — | 10 Months | Chronic blood loss led to augmented production of hematopoietic microenvironment, reduction in bone formation and activation of the bone resorption | Mouse |
| 7. | 17618464 | Kim109 | 2007 | Mouse dental follicle cells | — | — | 3 Weeks | All dental mesenchymal/follicle cells formed bone-like structures | Mouse |
| 8. | 17371295 | Yu48 | 2007 | Rat dental pulp stem cells, rat BMSCs/apical bud cells | — | Gelatin | 2 Weeks | Dental pulp stem cell/apical cell combinations showed normal morphology while BMSC/apical bud cell showed atypical morphology without enamel | Rat |
| 9. | 12755333 | Braut111 | 2003 | Mouse dental pulp cells | — | — | 2 Weeks | Transplanted tissues contained mineralized islands with osteocyte - like cells embedded within the atubular - mineralized matrix | Mouse |
| 10. | 12202005 | Gurevich112 | 2002 | Rat and Mouse BMSCs | — | Fibrin-based microbeads | 4 Weeks | BMSCs without expansion sporadically formed bone, while BMSCs after expansion on fibrin-based microbeads reliably formed bone | Mouse |
| 11. | 11341327 | Berger113 | 2001 | Mouse BMSCs | Estradiol 17β, dihydrotestosterone | — | 3 Weeks | BMSCs derived from male and female donors and transplanted in the kidney capsule respond to sex hormones with gender specific properties | Mouse |
EDTA, ethylenediaminetetraacetic acid.