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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Int J Biol Macromol. 2011 Dec 23;50(3):725–733. doi: 10.1016/j.ijbiomac.2011.12.012

Fig. 1.

Fig. 1

Domain organization and phylogenetic analysis of T. gondii Type I and II J-domain proteins. (A) Domain and motif organization of yeast Sis1 and T. gondii putative type II Hsp40s. Domains and motifs were identified by NCBI (http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi) and Motif Scan (http://myhits.isb-sib.ch/cgi-bin/motif_scan). (B) Neighbor joining (NJ) tree of Type I and II J-domain protein amino acid sequences of T. gondii, P. falciparum, S. cerevisiae Sis1, and human Hdj1. T. gondii sequences were included on the basis of gene ID release 4 (see Table 1). P. falciparum gene IDs begin with PF except Malp13P1.277. Frame indicates cluster of sequences related to Sis1/Hdj1. Type I and II sequences were analyzed because Sis1-like Hsp40 share the CTD domain present in type I Hsp40s.