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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Ultrasound Med Biol. 2012 Feb 15;38(4):626–641. doi: 10.1016/j.ultrasmedbio.2012.01.004

Table 1.

Results of pixel-by-pixel lesion classification for parameters based on RF data analysis of all specimens (n = 12), including the area under the receiver-operating characteristic curves (ROC AUC) in Fig. 5A, the maximum accuracy ACCmax. The temporal extrema (temp. max. or temp. min) of each parameter at each spatial location were determined using Eq. (11). The listed uncertainties are standard deviations due to the random variation of the specimens (Type A uncertainty).

Parameter Symbol ROC
AUC		 ACCmax Threshold
θ0 at mean
ACCmax
IBS change (temp. max.) [dB] ΔIBSmax 0.91±0.04 0.85±0.08 12
Midband-fit change (temp. max.) [dB] ΔMmax 0.88±0.08 0.83±0.12 11
Intercept change (temp. max.) [dB] ΔImax 0.87±0.11 0.81±0.12 31
Line-to-line echo-decorrelation (temp. max.) σmax 0.85±0.08 0.83±0.07 1.3
Initial-to-current-line echo-decorrelation (temp. max.) σI max 0.84±0.07 0.82±0.09 1.5
Slope change (temp. min.) [dB/MHz] Δmmin 0.82±0.07 0.81±0.11 −0.50
Midband fit change [dB] ΔM 0.73±0.14 0.71±0.15 3.3
Intercept change [dB] ΔI 0.73±0.13 0.70±0.14 7.8
IBS change [dB] ΔIBS 0.72±0.13 0.71±0.14 3
Initial-to-current-line echo decorr. σI 0.70±0.14 0.72±0.17 0.80
Slope change [dB/MHz] Δm 0.68±0.11 0.67±0.15 −0.17