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. 2012 Feb 28;27(1):13–19. doi: 10.3904/kjim.2012.27.1.13

Figure 1.

Figure 1

Pathophysiology of ascites and circulatory dysfunction in portal hypertension. The initial event is splanchnic arterial vasodilation, which causes effective hypovolemia. When circulatory dysfunction is moderate, patients develop sodium retention. When it is severe, patients develop a profound impairment in free water excretion and dilutional hyponatremia [10].