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Known TLRs, ligands for these TLRs and the relevant signalling pathways.
| TLR | Recognises | Signals through |
|---|---|---|
| 1 | Triacyl lipopeptides | TIRAP-MyD88 |
| 2 | Tri- and diacyl lipopeptides | Mal/TIRAP-MyD88 |
| 3 | dsRNA | TRIF-MyD88 independent |
| 4 | LPS | Mal/TIRAP-MyD88 & TRIF- MyD88 independent |
| 5 | Flagellin | MyD88 |
| 6 | Diacyl lipopeptides | TIRAP-MyD88 |
| 7 | ssRNA | MyD88 |
| 8 | ssRNA | MyD88 |
| 9 | CpG-DNA (bacterial origin and host derived apoptotic DNA fragments) | MyD88 |
| 10 | Undefined | Undefined |
