Table 3. General Amino Acid Control (GAAC) - Gcn4-controlled genes linked to amino acid biosynthesis.
Pathway | Genes |
---|---|
Histidine | HIS1, HIS2, HIS3, HIS4, HIS5, HIS7 |
Glutamate/Glutamine | GLT1, GDH2 |
Proline | PRO2 |
Arginine | ARG1, ARG2, ARG3, ARG4, ARG5, 6, ARG7, ARG8, ARG80, CPA1, CPA2 |
Lysine | LYS1, LYS2, LYS4, LYS5, LYS9, LYS12, LYS14, LYS20, LYS21 |
Aromatic (Phe, Trp, Tyr) | ARO1, ARO2, ARO3, ARO4, ARO8, ARO9, ARO10, TRP2, TRP3, TRP4, TRP5 |
Serine/Glycine | SER1, SER3, SER33, ICL1, AGX1, GCV1, GCV2, GCV3, LPD1, SHM2 |
Aspartate | AAT2 |
Asparagine | ASN1, ASN2 |
Threonine | HOM2, HOM3, THR1, THR4 |
Methionine | SUL1, SUL2, MET1, MET2, MET3, MET4, MET10, MET13, MET14, MET16, MET17, MET22, MET28 |
Branched chain (Leu, Ile, Val) | ILV1, ILV2, ILV3, ILV6, LEU1, LEU4, BAT1, BAT2, LEU3 |
Alanine | ALT1 |
TCA cycle | ACO2, IDP1, CIT3, RTG3 |
NCR | GLN3, GAT1 |
Data are from (Natarajan et al. (2001). Genes in boldface type encode transcription factors.