Table 5 . Analysis of mutational events.
| Average median frequency of respiration loss | Average rate of erythromycin resistance | Average rate of canavanine resistance | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Strains | % | Fold change | P-value | Rate (× 108) | Fold change | P-value | Rate (× 108) | Fold change | P-value |
| Wild type | 2.3 | — | — | 10.6 | — | — | 22.2 | — | — |
| mrx-Δ | 5.4 | 2.4 | 3.2 × 10−4 | 9.4 | 1.1 | 0.3 | 52.1 | 2.3 | 1.1 × 10−3 |
| ku70/80-Δ | 1.8 | 1.2 | 0.5 | 10.4 | 1.0 | 0.9 | 23.1 | 1.0 | 0.8 |
| mrx-Δ ku70/80-Δ | 8.0 | 3.5 | 2.6 × 10−3 | 0.9a | 12.3 | 0.01 | 47.8 | 2.2 | 2.1 × 10−4 |
a
At least one rate was calculated using the method of Luria and Delbruck (1943).