Table 1. Irradiated p53 mutants have significantly reduced survival rates.

	yw (1086)	yw+IR (572)	p53 (952)	p53+IR (1679)
% differentiated	99±1	99±1	99±1	78±5
% eclosed	99±1	83±3	99±1	11±7

Both irradiated (40 Gy at 96 hours AEL) and unirradiated yw controls and p53 mutant animals were assayed for differentiation during pupal stages (determined by cuticle deposition), as well as successful eclosion from pupal cases. Unirradiated larvae differentiate and eclose with nearly a 100% success rate and irradiated yw larvae differentiate and eclose with a very high level of success. Percentages of differentiating p53 mutants are lower following IR (78%) and irradiated mutants are highly deficient in eclosion (11%). Values represent percentage ± standard deviation, number of animals scored are in parentheses.