(b)

Gene	Fold downregulation 20 μg/mL	Fold downregulation 40 μg/mL	Assay ID	Function
ANKRD12	3.83 ± 1.84	21.63 ± 6.80	Hs00209530_m1	Ion channel inhibitor
ASPM	2.36 ± 0.63	5.69 ± 2.34	Hs00996458_m1	Calmodulin binding
CDC2	5.50 ± 2.22	9.39 ± 4.12	Hs00938777_m1	Protein binding
CDC25A	15.65 ± 3.26	2.09 ± 1.78	Hs00947994_m1	Phosphatase activity
CDCA4	7.98 ± 2.45	3.34 ± 1.85	Hs00743989_s1	Cell division
CENPE	78.27 ± 25.90	52.49 ± 16.37	Hs00156507_m1	Chromatin binding
CHEK1	24.20 ± 3.23	60.16 ± 29.80	Hs00176236_m1	Protein Kinase
COL12A1	3.62 ± 0.59	2.64 ± 1.23	Hs00329355_s1	Structural molecule
DLGAP5	12.34 ± 5.89	4.78 ± 2.63	Hs00207323_m1	Phosphatase activity
DPP4	15.39 ± 4.21	15.78 ± 2.62	Hs00175218_m1	Aminopeptidase
DTL	3.88 ± 1.40	1.55 ± 0.80	Hs00978565_m1	Protein binding
E2F8	75.55 ± 30.92	80.34 ± 19.30	Hs00226635_m1	Transcription factor
EBP	9.75 ± 3.21	3.26 ± 1.05	Hs00198130_m1	Sterol isomerase
FBXO5	4.25 ± 2.17	3.75 ± 0.54	Hs00559989_m1	Protein binding
FOLH1	5.92 ± 2.39	5.23 ± 1.31	Hs00379515_m1	Carboxypeptidase
HIST1H4C	8.34 ± 5.41	2.73 ± 0.73	Hs00543883_s1	DNA binding
HSP90B1	26.21 ± 12.03	30.88 ± 13.74	Hs00427665_g1	Nucleotide binding
ITGAV	13.50 ± 2.31	2.68 ± 1.86	Hs00233790_m1	Receptor
KIF14	1.93 ± 1.24	15.28 ± 4.89	Hs00208408_m1	Microtubule motor
MAD2L1	5.55 ± 3.25	7.83 ± 2.16	Hs01554515_g1	Protein binding
METAP2	5.04 ± 1.20	15.45 ± 5.21	Hs01127366_m1	Aminopeptidase
NRIP1	24.88 ± 6.20	45.47 ± 14.54	Hs00942766_s1	Transcription coactivator
POLA1	15.62 ± 3.22	4.39 ± 2.87	Hs00213524_m1	Nucleotide binding
PRIM2	11.83 ± 5.41	2.32 ± 0.33	Hs00386277_m1	DNA primase
RRM1	5.87 ± 1.72	11.23 ± 4.21	Hs01040698_m1	Ribonucleoside diphosphate reductase
SKP2	17.52 ± 11.90	16.43 ± 4.23	Hs00180634_m1	Ubiquitin-protein ligase
TOP2A	15.53 ± 3.89	10.34 ± 2.11	Hs01032127_g1	Topoisomerase activity
TOP2B	2.03 ± 1.48	2.25 ± 0.79	Hs00172259_m1	Topoisomerase activity
TPR	1.35 ± 1.91	4.66 ± 1.30	Hs00162918_m1	Protein kinase
UHRF1	10.73 ± 2.84	3.41 ± 1.52	Hs00273589_m1	Transcription factor