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. Author manuscript; available in PMC: 2012 Jun 30.
Published in final edited form as: Respir Physiol Neurobiol. 2011 Feb 25;177(1):1–8. doi: 10.1016/j.resp.2011.02.010

Fig 1.

Fig 1

Charybdotoxin (MaxiK channel blocker) minimally alters the chemoreceptor response to hypoxia in mature (P18) chemoreceptor. A: polygraphic recording of experimental run. Top trace: chamber O2 tension. Bar indicates period of sham-drug perfusion. Bottom trace: raw recording of action potential (AP) activity recorded from a petrosal chemoreceptor neuron with time on the abscissa and voltage on the ordinate. S1, S2 and S3 are stimulus artifacts during electrical stimulation to the carotid body for orthodromic AP initiation. B: frequency/PO2 response relationship for chemoreceptor before (open circle), during (open triangle) and following (filled square) sham drug perfusion. Exponential line fits using least-square methods. C: expanded overlaid traces during orthodromic stimulation from S1 to S3 showing no change in conduction time.