Table 1.
PWS | Control | p value | ||||
---|---|---|---|---|---|---|
Mean (SD) | DEL | UPD | HWC | DEL vs HWC | UPD vs HWC | UPD vs DEL |
N | 15 | 8 | 25 | |||
Age (years) | 25.2 (13.6) | 17.4 (6.5) | 22.3 (10.8) | 0.465 | 0.233 | 0.143 |
Sex (female: male) | 12:3 | 3:5 | 14:11 | 0.123 | 0.362 | 0.042 |
Body mass index | 33.0 (8.6) | 29.8 (10.2) | 20.7 (2.8) | <.001 | <.001 | 0.425 |
IQ | 60.1 (8.2) | 69.8 (13.1) | 118.4 (11.1)° | <.001 | <.001 | 0.042 |
| ||||||
Global Brain Volumes, mean volume, ×103 mm3 (SD) | ||||||
| ||||||
GMV | 646 (29) | 695 (67) | 719 (63) | <.001 | 0.36 | 0.025 |
WMV | 458 (26) | 461 (41) | 511 (46) | <.001 | 0.012 | 0.832 |
CSF | 286 (32) | 287 (39) | 298 (26) | 0.193 | 0.362 | 0.947 |
TICV | ||||||
(GM + WM + CSF) | 1391 (73) | 1444 (142) | 1529 (126) | <.001 | 0.115 | 0.249 |
IQ was only collected on 10 out of 25 HWC individuals