Table 2.
GMV differences between Prader-Willi Group (combined) and Healthy Controls
| Talairach Region | Peak Coordinate | k | Z Score | p Value | |||
|---|---|---|---|---|---|---|---|
| HWC > PWS | x | y | z | FWE | uncor | ||
| R Inferior Frontal Gyrus (BA 45) | 56 | 39 | 8 | 3064 | 3.58 | 0.692 | 0.000 |
| R Middle Frontal Gyrus | 44 | 27 | 31 | 1080 | 3.92 | 0.330 | 0.000 |
| L Middle Frontal Gyrus (BA 8) | −26 | 22 | 51 | 895 | 3.9 | 0.348 | 0.000 |
| * L/R Anterior Cingulate Gyrus | 2 | 14 | 26 | 9319 | 4.84 | 0.012 | 0.000 |
| *L Superior Temporal Gyrus/ L Parahippocampal Gyrus/ L Hippocampus | −48 | 13 | −7 | 99130 | 5.53 | 0.001 | 0.000 |
| R Precentral Gyrus (BA 4) | 32 | −22 | 48 | 207 | 3.5 | 0.775 | 0.000 |
| *R Superior Temporal Gyrus (BA 22)/ R Parahippocampal Gyrus/ R Hippocampus | 66 | −35 | 6 | 75006 | 5.58 | 0.000 | 0.000 |
| L Cerebellum | −42 | −67 | −48 | 1480 | 3.63 | 0.636 | 0.000 |
Listed Rostral to Caudal for each analysis; R= right, L= left, BA= Brodmann’s Area, uncor = uncorrected, k=cluster size, FWE= family wise error
*
Significant at p < .05 FWE corrected in bold, clusters include all regions separated by a (/).