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. 2012 Feb 6;13:7. doi: 10.1186/1471-2156-13-7

Table 3.

Power for all tests in simulated data of scenario C weak common SNPs effect, effects of RVs are in the same direction

OR 1.3 1.6 1.9 2.2 2.5 2.8 3.1
Rind 0.237 0.394 0.472 0.6 0.715 0.785 0.843

Rsum 0.247 0.418 0.543 0.636 0.747 0.811 0.869

Cbon 0.163 0.157 0.144 0.164 0.174 0.191 0.193

Clogit 0.195 0.199 0.193 0.207 0.212 0.228 0.238

Bind 0.278 0.364 0.436 0.517 0.618 0.677 0.76

Bsum 0.298 0.384 0.461 0.562 0.668 0.735 0.795

RindSC 0.236 0.43 0.565 0.702 0.781 0.888 0.91

RsumSC 0.238 0.446 0.605 0.705 0.815 0.892 0.92

BwSum 0.341 0.534 0.658 0.703 0.846 0.87 0.911

BwOR 0.253 0.312 0.344 0.475 0.456 0.582 0.648

BKML 0.167 0.186 0.186 0.19 0.204 0.199 0.2

BSSU 0.165 0.179 0.179 0.181 0.192 0.192 0.188

BSSUw 0.203 0.334 0.458 0.61 0.716 0.808 0.861

BaSSU 0.168 0.215 0.235 0.28 0.303 0.34 0.383

BaSSUw 0.181 0.346 0.399 0.546 0.64 0.755 0.819

BaSSUOrd 0.163 0.293 0.376 0.571 0.592 0.733 0.798

BaSSUwOrd 0.238 0.367 0.506 0.663 0.732 0.847 0.89

BwSCd 0.21 0.395 0.484 0.625 0.661 0.822 0.848

BwSC 0.344 0.538 0.631 0.778 0.85 0.935 0.954

There is customized LD structure among common variants and among rare variants.

The OR for underlying common SNP is 1.5. Genetic effect parameter OR for eight rare variants is listed in the table. If OR is 2, Odds Ratio = (2, 2, 2, 2, 3, 3, 3, 3) for eight casual rare variants. Notations of tests are defined similarly as those in Table 1.