Table 2.
Thiobarbituric acid-reactive substances (TBARS) and lactate dehydrogenase (LDH) activity in brain, liver and plasma of different experimental groups.
| Parameter | Experimental groups | |||||
|---|---|---|---|---|---|---|
| Control | AlCl3 | AlCl3+FSP | AlCl3+FSE | FSP | FSE | |
| Brain | ||||||
| TBARS | 3.43 ± 0.35 | 6.12a* ± 0.12 | 3.76b* ± 0.21 | 2.46b* ± 0.28 | 4.07 ± 0.02 | 4.15 ± 0.37 |
| LDH | 84.9 ± 1.27 | 115.8a ± 7.21 | 86.4b ± 3.65 | 93.3a*b ± 0.20 | 83.05 ± 1.58 | 83.13 ± 2.64 |
| Liver | ||||||
| TBARS | 2.15 ± 0.18 | 3.11a ± 0.24 | 2.75 ± 0.20 | 2.32b ± 0.15 | 3.02a ± 0.07 | 2.88a ± 0.25 |
| LDH | 191.4 ± 6.45 | 282.2a* ± 11.2 | 199.9b*c* ± 0.80 | 185.5b*c* ± 2.62 | 195.7 ± 3.49 | 184.9 ± 0.30 |
| Plasma | ||||||
| TBARS | 0.82 ± 0.03 | 1.21a ± 0.09 | 0.79b ± 0.02 | 0.91b ± 0.02 | 0.88 ± 0.01 | 1.05a* ± 0.02 |
| LDH | 485.5 ± 14.0 | 1071.5a* ± 5.59 | 891.5a*b* ± 20.3 | 914.0a*b* ± 0.01 | 575.5 ± 120.0 | 463.0 ± 30.8 |
Values are expressed as means ± SD; n = 10 for each treatment group.
a Significant difference from the control group at p < 0.05.
b Significant difference from the AlCl3-intoxicated group at p < 0.05.
c Significant difference between AlCl3+FSP and AlCl3+FSE groups at p < 0.05.
* p < 0.001.
In brain and liver TBARS and LDH are expressed respectively as: nmol MDA/mg protein and UI/g of tissue; in plasma TBARS and LDH are expressed respectively as: nmol MDA/l and UI/l.