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Failure of inhaled heparin disaccharide to inhibit allergic bronchoconstrictor responses in sheep. Top: Antigen-induced % change in specific lung resistance (SRL) ± SE in "Acute Responders" with (4 mg/kg; n = 3) and without pretreatment (control). Bottom: "Dual Responders" (1 mg/kg, n = 3,) without (control; open circles) and after treatment (solid circles) with inhaled disaccharide.
